Targets of perturbagens

Perturbagen ID : CID57543

Perturbagen : (-)-cocaine; (−)-cocaine; 2-methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester); [1r-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester; Benzoylmethylecgonine; Beta-cocain; Cocain; Cocaina; Cocaine; Cocaine hydrochloride; Cocainum; Kokain; L-cocain; L-cocaine; Methyl [1r-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate; Methyl benzoylecgonine; Neurocaine

Target	Effect	Reference
CHRM1	-1	DrugBank; STITCH
CHRM2	-1	DrugBank; STITCH
CXCL8	-1	STITCH
GRM5	-1	STITCH
SCN10A	-1	DrugBank; STITCH
SCN11A	-1	DrugBank; STITCH
SCN5A	-1	DrugBank; STITCH
SLC6A2	-1	DrugBank; STITCH
SLC6A3	-1	DrugBank; STITCH
SLC6A4	-1	DrugBank; STITCH
TNF	-1	STITCH
ACE	1	STITCH
BDNF	1	STITCH
CCL2	1	STITCH
CREB1	1	STITCH
DRD3	1	STITCH
EGR1	1	STITCH
FOS	1	STITCH
HTR2A	1	STITCH
OPRK1	1	STITCH
OPRM1	1	STITCH
PDYN	1	STITCH
POMC	1	STITCH
TH	1	STITCH
BCHE	2	STITCH
CAMK4	2	STITCH
CARTPT	2	STITCH
CD81	2	STITCH
CES1	2	DrugBank; STITCH
CES2	2	STITCH
CES5A	2	STITCH
CHRFAM7A	2	STITCH
CHRNA1	2	STITCH
CHRNA10	2	STITCH
CHRNA2	2	STITCH
CHRNA3	2	STITCH
CHRNA4	2	STITCH
CHRNA5	2	STITCH
CHRNA6	2	STITCH
CHRNA7	2	STITCH
CHRNA9	2	STITCH
CHRNB1	2	STITCH
CHRNB2	2	STITCH
CHRNB3	2	STITCH
CHRNB4	2	STITCH
CHRND	2	STITCH
CXCL10	2	STITCH
CYP3A4	2	STITCH
CYP3A5	2	STITCH
CYP3A7	2	STITCH
DBH	2	STITCH
DRD2	2	STITCH
DRD4	2	STITCH
GRIN1	2	STITCH
HOMER1	2	STITCH
HTR1A	2	STITCH
HTR3A	2	STITCH
HTR3B	2	STITCH
HTR3C	2	STITCH
HTR3D	2	STITCH
HTR3E	2	STITCH
IL10	2	STITCH
KCNH2	2	STITCH
MGMT	2	STITCH
PPP1R1B	2	STITCH
PRL	2	STITCH
SIGMAR1	2	DrugBank
SLC18A1	2	STITCH
SLC6A1	2	STITCH
SLC6A11	2	STITCH
SLC6A12	2	STITCH
SLC6A13	2	STITCH
SLC6A15	2	STITCH
SLC6A16	2	STITCH
SLC6A17	2	STITCH
SLC6A18	2	STITCH
SLC6A19	2	STITCH
SLC6A20	2	STITCH
SLC6A5	2	STITCH
SLC6A7	2	STITCH
SLC6A8	2	STITCH
SLC6A9	2	STITCH
TACR3	2	STITCH
TNNI3	2	STITCH