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Perturbagen
Expression Profiles
Transcriptional Responses
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Overview
Perturbagen
Expression Profiles
Transcriptional Responses
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Targets of perturbagens
Perturbagen ID : CID57386
Perturbagen : 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5h-dibenzo(a,d)cycloheptene; 10,11-dihydro-n,n-dimethyl-5h-dibenzo(a,d)heptalene-delta(5),gamma-propylamine; 3-(10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5-ylidene)-n,n-dimethyl-1-propanamine; 3-(10,11-dihydro-5h-dibenzo[a,d]cyclohepten-5-ylidene)-n,n-dimethylpropan-1-amine; 5-(3-dimethylaminopropylidene)-10,11-dihydro-5h-dibenzo(a,d)cycloheptatriene; 5-(3-dimethylaminopropylidene)-10,11-dihydro-5h-dibenzo(a,d)cycloheptene; 5-(gamma-dimethylaminopropylidene)-5h-dibenzo[a,d][1,4]cycloheptadiene; Amitriptilina; Amitriptylin; Amitriptyline; Amitriptyline 10 tab; Amitriptyline 25 tab; Amitriptyline hydrochloride; Amitriptyline-10; Amitriptyline-25; Amitriptyline-50; Amitriptylinum; Apo peram tab 2-25; Apo peram tab 3-15; Apo-amitriptyline; Bio-amitriptyline; Chlordiazepoxide and amitriptyline hcl; Chlordiazepoxide and amitriptyline hydrochloride; Dom-amitriptyline; Elavil; Elavil plus tab; Equipto - amitriptyline external cream compounding kit; Etrafon 2 10; Etrafon a tab; Etrafon d tab; Etrafon f tab; Gpc-amitriptyline; Ipg-amitriptyline; Jamp-amitriptyline; Jamp-amitriptyline tablets; Levate; Mar-amitriptyline; Nu-amitriptyline tablets; Perphenazine and amitriptyline hydrochloride; Pms-amitriptyline; Pms-levazine 2/25 tab; Pms-levazine 3/15 tab; Pms-levazine 4/25 tab; Proavil tab; Teva-amitriptyline; Triavil tab
Target
Effect
Reference
ADRA1A
-1
DrugBank; CLUE; STITCH
ADRA1B
-1
DrugBank; CLUE; STITCH
ADRA1D
-1
DrugBank; CLUE; STITCH
ADRA2A
-1
DrugBank; CLUE; STITCH
ADRB1
-1
CLUE; STITCH
ADRB2
-1
CLUE; STITCH
ADRB3
-1
CLUE; STITCH; DrugBank
CALM1
-1
DrugBank
CHRM1
-1
DrugBank; CLUE; STITCH
CHRM2
-1
DrugBank; CLUE; STITCH
CHRM3
-1
DrugBank; CLUE; STITCH
CHRM4
-1
DrugBank; CLUE; STITCH
CHRM5
-1
DrugBank; CLUE; STITCH
CYP2D6
-1
STITCH
DRD1
-1
DrugBank
DRD2
-1
DrugBank
GSTP1
-1
STITCH
HRH1
-1
DrugBank; CLUE; STITCH
HRH2
-1
DrugBank; CLUE; STITCH
HRH4
-1
CLUE; STITCH; DrugBank
HTR1A
-1
DrugBank; CLUE; STITCH
HTR1B
-1
CLUE; STITCH; DrugBank
HTR1D
-1
CLUE; STITCH; DrugBank
HTR2A
-1
DrugBank; CLUE; STITCH
HTR2C
-1
CLUE; STITCH; DrugBank
HTR6
-1
DrugBank; CLUE; STITCH
HTR7
-1
DrugBank; CLUE; STITCH
KCNA1
-1
DrugBank; CLUE; STITCH
KCND2
-1
DrugBank; CLUE; STITCH
KCND3
-1
DrugBank; CLUE; STITCH
KCNQ2
-1
DrugBank; CLUE; STITCH
KCNQ3
-1
CLUE; STITCH; DrugBank
NTRK1
-1
CLUE; STITCH; DrugBank
NTRK2
-1
CLUE; STITCH; DrugBank
OPRD1
-1
CLUE; STITCH; DrugBank
OPRK1
-1
CLUE; STITCH; DrugBank
OPRM1
-1
CLUE; STITCH; DrugBank
SIGMAR1
-1
CLUE; STITCH; DrugBank
SLC6A2
-1
DrugBank; CLUE; STITCH
SLC6A4
-1
DrugBank; CLUE; STITCH
GABRQ
1
DrugBank
SREBF1
1
STITCH
SREBF2
1
STITCH
ADRA2C
2
STITCH
CYP1A2
2
STITCH
CYP2C19
2
STITCH
CYP2C9
2
STITCH
CYP3A4
2
STITCH
CYP3A5
2
STITCH
DRD3
2
STITCH
DRD5
2
STITCH
HTR2B
2
STITCH
ORM1
2
STITCH
ORM2
2
STITCH
SLC6A3
2
STITCH