Targets of perturbagens

Perturbagen ID : CID56874

Perturbagen : (−)-etoposide; 4'-demethylepipodophyllotoxin 9-(4,6-o-(r)-ethylidene-beta-d-glucopyranoside); 4-demethylepipodophyllotoxin β-d-ethylideneglucoside; 9-((4,6-o-ethylidine-beta-d-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5ah)-one; Dom-etoposide; Eposin; Etopophos; Etoposide; Etoposide injection; Etoposide injection usp; Etoposide injection, usp; Etoposido; Etoposidum; Pms-etoposide; Toposar; Trans-etoposide; Vepesid

Target	Effect	Reference
CYP2E1	-1	CLUE; STITCH
CYP3A5	-1	CLUE; STITCH
TOP2A	-1	DrugBank; CLUE; STITCH
TOP2B	-1	DrugBank; CLUE; STITCH
AKT1	1	STITCH
ATF2	1	STITCH
BAK1	1	STITCH
BCL2L1	1	STITCH
CASP3	1	STITCH
CASP7	1	STITCH
CASP8	1	STITCH
CASP9	1	STITCH
CAT	1	STITCH
CDKN1A	1	STITCH
CYCS	1	STITCH
FAS	1	STITCH
FASLG	1	STITCH
H2AFX	1	STITCH
H2AX	1	STITCH
HIPK2	1	STITCH
MAPK12	1	STITCH
MYC	1	STITCH
NR1I2	1	STITCH
PRKCD	1	STITCH
TP53	1	STITCH
ABCB1	2	STITCH
ABCC1	2	STITCH
ABCC2	2	STITCH
ABCC3	2	STITCH
ABCG2	2	STITCH
ALB	2	STITCH
APAF1	2	STITCH
APEX1	2	STITCH
AR	2	STITCH
ARL6IP5	2	STITCH
ATP7A	2	STITCH
BAX	2	STITCH
BCL2L2	2	STITCH
BID	2	STITCH
BIK	2	STITCH
BIN1	2	STITCH
BIRC2	2	STITCH
BIRC3	2	STITCH
BIRC5	2	STITCH
BIRC7	2	STITCH
CALCA	2	STITCH
CASP2	2	STITCH
CASP6	2	STITCH
CCDC6	2	STITCH
CD40LG	2	STITCH
CEBPA	2	STITCH
CHEK2	2	STITCH
CHI3L1	2	STITCH
CIAPIN1	2	STITCH
CYP3A4	2	STITCH
DCK	2	STITCH
DNMT1	2	STITCH
DNMT3B	2	STITCH
EIF3A	2	STITCH
ERBB2	2	STITCH
ESR2	2	STITCH
ETV6	2	STITCH
FOXO1	2	STITCH
FOXO3	2	STITCH
GADD45A	2	STITCH
GSTP1	2	STITCH
IL4	2	STITCH
KEAP1	2	STITCH
KMT2A	2	STITCH
LMNB1	2	STITCH
MAPK1	2	STITCH
MAPK3	2	STITCH
MAPK8	2	STITCH
MCL1	2	STITCH
MPO	2	STITCH
MYCN	2	STITCH
NFKBIA	2	STITCH
PARP1	2	STITCH
PPP1R13L	2	STITCH
PRKCZ	2	STITCH
PRKDC	2	STITCH
PRNP	2	STITCH
PTEN	2	STITCH
RASSF1	2	STITCH
RB1	2	STITCH
RBM17	2	STITCH
RPL6	2	STITCH
RUNX1	2	STITCH
RUNX3	2	STITCH
S100P	2	STITCH
SMAD2	2	STITCH
SOD2	2	STITCH
SP1	2	STITCH
TMSB4X	2	STITCH
TPI1	2	STITCH
TXN2	2	STITCH
UGT1A1	2	STITCH
UGT1A3	2	STITCH
UGT1A8	2	STITCH
UNC5C	2	STITCH
VCAM1	2	STITCH
VEGFA	2	STITCH
WIF1	2	STITCH
WNT3A	2	STITCH
WRN	2	STITCH
XAF1	2	STITCH
XRCC4	2	STITCH
ZNRD1	2	STITCH