Targets of perturbagens

Perturbagen ID : CID56867

Perturbagen : (1s,3s)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranoside; (8s-cis)-10-((3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; 14-hydroxydaunomycin; 14-hydroxydaunorubicine; Adriamycin; Adriamycin pfs; Adriamycin rdf; Caelyx; Doxil; Doxorubicin; Doxorubicin hydrochloride; Doxorubicin hydrochloride for injection, usp; Doxorubicin hydrochloride injection; Doxorubicin hydrochloride injection, usp; Doxorubicin hydrochloride liposome; Doxorubicin injection; Doxorubicine; Doxorubicinum; Hydroxydaunorubicin; Myocet

Target	Effect	Reference
CDC25C	-1	STITCH
CDK1	-1	STITCH
CHD1	-1	STITCH
CYP2D6	-1	STITCH
FOXO1	-1	STITCH
FOXO3	-1	STITCH
HIF1A	-1	STITCH
LGALS3	-1	STITCH
NR3C1	-1	STITCH
PCNA	-1	STITCH
PLAU	-1	STITCH
SOD2	-1	STITCH
TGFB1	-1	STITCH
THBS1	-1	STITCH
TOP2A	-1	DrugBank; CLUE; STITCH
TOP2B	-1	STITCH
ABCB1	1	STITCH
ABCC1	1	STITCH
ABCG2	1	STITCH
AKT1	1	STITCH
ATM	1	STITCH
BAK1	1	STITCH
BID	1	STITCH
BIK	1	STITCH
BIRC3	1	STITCH
CASP2	1	STITCH
CASP3	1	STITCH
CASP6	1	STITCH
CASP7	1	STITCH
CASP8	1	STITCH
CASP9	1	STITCH
CDKN1A	1	STITCH
CHEK1	1	STITCH
CHEK2	1	STITCH
EDN1	1	STITCH
EGFR	1	STITCH
FAS	1	STITCH
GATA1	1	STITCH
GPX1	1	STITCH
H2AFX	1	STITCH
H2AX	1	STITCH
HIPK2	1	STITCH
HSPB1	1	STITCH
HSPB2-C11orf52	1	STITCH
MAPK1	1	STITCH
MAPK14	1	STITCH
MAPK3	1	STITCH
MAPK8	1	STITCH
MAPK9	1	STITCH
MYC	1	STITCH
MYCN	1	STITCH
NFKB1	1	STITCH
PARP1	1	STITCH
POR	1	STITCH
PRKCD	1	STITCH
PTEN	1	STITCH
PTGS2	1	STITCH
RELA	1	STITCH
TP53	1	STITCH
VEGFA	1	STITCH
ABCB4	2	STITCH
ABCB5	2	STITCH
ABCC3	2	STITCH
AKR1A1	2	STITCH
AKR1B10	2	STITCH
AKR1C3	2	STITCH
AKR7A2	2	STITCH
ALDH1A2	2	STITCH
ALDH2	2	STITCH
ANGPT1	2	STITCH
API5	2	STITCH
ATP7A	2	STITCH
AURKA	2	STITCH
BACH1	2	STITCH
BAD	2	STITCH
BCL2	2	STITCH
BCL2L1	2	STITCH
BIN1	2	STITCH
BIRC5	2	STITCH
BIRC6	2	STITCH
BTG2	2	STITCH
BUB3	2	STITCH
CACYBP	2	STITCH
CBR1	2	STITCH
CCND1	2	STITCH
CD40LG	2	STITCH
CDK2	2	STITCH
CDKN1B	2	STITCH
CDY1	2	STITCH
CEBPB	2	STITCH
CFTR	2	STITCH
CHI3L1	2	STITCH
CHUK	2	STITCH
CIAPIN1	2	STITCH
CITED2	2	STITCH
CLU	2	STITCH
CRYAA	2	STITCH
CRYAB	2	STITCH
CTNNB1	2	STITCH
CTSD	2	STITCH
CYLD	2	STITCH
DFFA	2	STITCH
DPP4	2	STITCH
EFNB3	2	STITCH
EIF3A	2	STITCH
ERBB2	2	STITCH
ERP29	2	STITCH
ETV6	2	STITCH
F2	2	STITCH
FASN	2	STITCH
FDFT1	2	STITCH
FKBP4	2	STITCH
FN1	2	STITCH
FOLR1	2	STITCH
FUBP1	2	STITCH
GDF15	2	STITCH
GFI1B	2	STITCH
GLO1	2	STITCH
GLRX	2	STITCH
GSK3B	2	STITCH
GSR	2	STITCH
GSTA1	2	STITCH
GSTP1	2	STITCH
H2BC4	2	STITCH
HGF	2	STITCH
HIST1H2BC	2	STITCH
HLA-DQB1	2	STITCH
HNRNPD	2	STITCH
HNRNPK	2	STITCH
HNRNPL	2	STITCH
IFNA1	2	STITCH
IKBKB	2	STITCH
JUN	2	STITCH
KCNA5	2	STITCH
KCNH2	2	STITCH
KDSR	2	STITCH
KEAP1	2	STITCH
KHSRP	2	STITCH
LMNA	2	STITCH
MAP2K1	2	STITCH
MAP2K2	2	STITCH
MAP2K4	2	STITCH
MAP3K8	2	STITCH
MCAM	2	STITCH
MCL1	2	STITCH
MDH2	2	STITCH
MDK	2	STITCH
MGMT	2	STITCH
MMP1	2	STITCH
MT-ND6	2	STITCH
MT2A	2	STITCH
MT3	2	STITCH
MTR	2	STITCH
NAIP	2	STITCH
ND6	2	STITCH
NFE2L2	2	STITCH
NFKBIA	2	STITCH
NME1	2	STITCH
NOLC1	2	DrugBank; STITCH
NONO	2	STITCH
NR4A1	2	STITCH
OXTR	2	STITCH
PARK7	2	STITCH
PDPK1	2	STITCH
PHLDA2	2	STITCH
PMAIP1	2	STITCH
PPP1R1B	2	STITCH
PRNP	2	STITCH
PROCR	2	STITCH
PSMA1	2	STITCH
PSMA2	2	STITCH
PSMA3	2	STITCH
PSMA4	2	STITCH
PSMA5	2	STITCH
PSMA6	2	STITCH
PSMA7	2	STITCH
PSMB2	2	STITCH
PSMB7	2	STITCH
PSMD10	2	STITCH
PSPC1	2	STITCH
RAB6C	2	STITCH
RALBP1	2	STITCH
RB1	2	STITCH
RBBP4	2	STITCH
RBL2	2	STITCH
RBM17	2	STITCH
RFC1	2	STITCH
RHOA	2	STITCH
RPL6	2	STITCH
RUNX1	2	STITCH
RUNX3	2	STITCH
S100P	2	STITCH
SARNP	2	STITCH
SAT1	2	STITCH
SCNN1G	2	STITCH
SLC22A16	2	STITCH
SLC9A1	2	STITCH
SOX17	2	STITCH
SPHK2	2	STITCH
SQSTM1	2	STITCH
SRI	2	STITCH
STAT1	2	STITCH
STIP1	2	STITCH
STX3	2	STITCH
TCF3	2	STITCH
TERT	2	STITCH
TMEM243	2	STITCH
TMSB4X	2	STITCH
TOMM20	2	STITCH
TRIM28	2	STITCH
TUBA4A	2	STITCH
TUBB4A	2	STITCH
UGCG	2	STITCH
WEE1	2	STITCH
XIAP	2	STITCH
XRCC3	2	STITCH
ZFP36L2	2	STITCH
ZNF394	2	STITCH
ZNRD1	2	STITCH
ZSCAN25	2	STITCH