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Targets of perturbagens

Perturbagen ID : CID56848

Perturbagen : (-)-buprenorphine; (−)-buprenorphine; 17-cyclopropylmethyl-4,5alpha-epoxy-7alpha-((s)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol; 2-(n-cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6alpha-yl)-3,3-dimethyl-2-butanol; 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14r)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol; 21-cyclopropyl-7alpha-[(s)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine; Act buprenorphine/naloxone; Belbuca; Bunavail; Buprenex; Buprenophine; Buprenorfina; Buprenorphine; Buprenorphine and naloxone; Buprenorphine hcl; Buprenorphine hcl and naloxone hcl; Buprenorphine hydrochloride; Buprenorphine hydrochloride and naloxone hydrochloride dihydrate; Buprenorphine hydrochloride sublingual; Buprenorphinum; Butrans; Butrans 10; Butrans 15; Butrans 20; Butrans 5; Mylan-buprenorphine/naloxone; Probuphine; Suboxone; Teva-buprenorphine/naloxone; Zubsolv

Target	Effect	Reference
CYP3A4	-1	STITCH
OPRD1	-1	DrugBank; STITCH
OPRK1	-1	DrugBank; STITCH
OPRM1	-1	DrugBank
TLR4	-1	DrugBank
CES1	2	DrugBank
CREB1	2	DrugBank
ESR1	2	DrugBank
MAPK1	2	STITCH
MAPK3	2	STITCH
OPRL1	2	DrugBank; STITCH
UGT1A1	2	STITCH