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Database
Overview
Perturbagen
Expression Profiles
Transcriptional Responses
Download
Documentation
Contact
Home
Webtool
Database
Overview
Perturbagen
Expression Profiles
Transcriptional Responses
Download
Documentation
Contact
Targets of perturbagens
Perturbagen ID : CID54765
Perturbagen : 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile; Bosulif; Bosulif®; Bosutinib; Bosutinib monohydrate; Ski 606
Target
Effect
Reference
ABL1
-1
DrugBank; CLUE; STITCH
ABL2
-1
STITCH
AXL
-1
STITCH
BCR
-1
DrugBank; CLUE; STITCH
BLK
-1
STITCH
BMX
-1
STITCH
BTK
-1
STITCH
CAMK1D
-1
CLUE; STITCH
CAMK2G
-1
DrugBank; CLUE; STITCH
CDK2
-1
DrugBank; CLUE; STITCH
CHEK1
-1
STITCH
CHEK2
-1
STITCH
CSF1R
-1
STITCH
CSK
-1
STITCH
CSNK1A1
-1
STITCH
CSNK1D
-1
STITCH
CSNK1E
-1
STITCH
EGFR
-1
STITCH
EPHA2
-1
STITCH
EPHA3
-1
STITCH
EPHA4
-1
STITCH
EPHA5
-1
STITCH
EPHA6
-1
STITCH
EPHA8
-1
STITCH
EPHB1
-1
STITCH
EPHB2
-1
STITCH
EPHB3
-1
STITCH
EPHB4
-1
STITCH
ERBB2
-1
STITCH
ERBB4
-1
STITCH
FER
-1
STITCH
FES
-1
STITCH
FGFR2
-1
STITCH
FGR
-1
STITCH
FLT1
-1
STITCH
FLT3
-1
STITCH
FLT4
-1
STITCH
FRK
-1
CLUE; STITCH
FYN
-1
CLUE; STITCH
HCK
-1
DrugBank; CLUE; STITCH
INSRR
-1
STITCH
IRAK4
-1
STITCH
LCK
-1
STITCH
LRRK2
-1
STITCH
LYN
-1
CLUE; STITCH; DrugBank
MAP2K1
-1
DrugBank; CLUE; STITCH
MAP2K2
-1
DrugBank; CLUE; STITCH
MAP3K10
-1
STITCH
MAP3K11
-1
STITCH
MAP3K2
-1
DrugBank; CLUE; STITCH
MAP3K20
-1
STITCH
MAP3K3
-1
STITCH
MAP3K7
-1
STITCH
MAP3K9
-1
STITCH
MAP4K2
-1
STITCH
MAP4K4
-1
STITCH
MAP4K5
-1
CLUE; STITCH
MELK
-1
STITCH
MERTK
-1
STITCH
MINK1
-1
STITCH
MYLK2
-1
STITCH
MYO3B
-1
STITCH
NEK1
-1
STITCH
NEK2
-1
STITCH
NEK4
-1
STITCH
NTRK2
-1
STITCH
NTRK3
-1
STITCH
NUAK1
-1
STITCH
NUAK2
-1
STITCH
PAK1
-1
STITCH
PAK3
-1
STITCH
PHKG1
-1
STITCH
PRKCA
-1
STITCH
PRKCD
-1
STITCH
PRKD1
-1
STITCH
PRKD2
-1
STITCH
PRKD3
-1
STITCH
PTK2B
-1
STITCH
RET
-1
STITCH
RPS6KA2
-1
STITCH
SIK2
-1
STITCH
SLK
-1
STITCH
SRC
-1
DrugBank; CLUE; STITCH
STK10
-1
CLUE; STITCH
STK24
-1
CLUE; STITCH
STK25
-1
STITCH
STK26
-1
STITCH
STK3
-1
STITCH
STK33
-1
STITCH
STK4
-1
CLUE; STITCH
SYK
-1
STITCH
TBK1
-1
STITCH
TNK2
-1
CLUE; STITCH
TXK
-1
CLUE; STITCH
TYRO3
-1
STITCH
WEE1
-1
STITCH
YES1
-1
STITCH
CAMK2A
2
STITCH
CLK3
2
STITCH
CTNNB1
2
STITCH
DDR1
2
STITCH
DDR2
2
STITCH
DMPK
2
STITCH
DSTYK
2
STITCH
EIF2AK4
2
STITCH
ERBB3
2
STITCH
GAK
2
STITCH
HIPK4
2
STITCH
KIT
2
STITCH
MAP2K5
2
STITCH
MAP3K19
2
STITCH
MAP3K4
2
STITCH
MAP4K1
2
STITCH
MAP4K3
2
STITCH
NTRK1
2
STITCH
PDGFRB
2
STITCH
PTK2
2
STITCH
SIK1
2
STITCH
SRMS
2
STITCH
STK35
2
STITCH
TEC
2
STITCH
TEK
2
STITCH
TNIK
2
STITCH
WEE2
2
STITCH