Targets of perturbagens

Perturbagen ID : CID54203

Perturbagen : (+)-camptothecin; (+)-camptothecine; (s)-(+)-camptothecin; (s)-camptothecin; 20(s)-camptothecin; 21,22-secocamptothecin-21-oic acid lactone; Camptothecin; Camptothecine; D-camptothecin

Target	Effect	Reference
TOP1	-1	CLUE; STITCH; DrugBank
HIF1A	-1	CLUE; STITCH
CDK2	-1	STITCH
DPYD	-1	STITCH
TP53	1	STITCH
BAX	1	STITCH
SP3	1	STITCH
CASP3	1	STITCH
SP1	1	STITCH
CASP8	1	STITCH
CASP7	1	STITCH
PPP1R1B	2	STITCH
THBS1	2	STITCH
RBL2	2	STITCH
IL1B	2	STITCH
RB1	2	STITCH
CXCL8	2	STITCH
ERCC4	2	STITCH
CASP2	2	STITCH
CLPTM1L	2	STITCH
PPP2R2A	2	STITCH
BCL2	2	STITCH
CASP9	2	STITCH
RAD51C	2	STITCH
PPP2R5E	2	STITCH
XRCC4	2	STITCH
XIAP	2	STITCH
PARP1	2	STITCH
JUN	2	STITCH
VEGFA	2	STITCH
SMN1	2	STITCH
SQSTM1	2	STITCH
GSTP1	2	STITCH
RELA	2	STITCH
CHEK1	2	STITCH
MAPK9	2	STITCH
PPP2R5C	2	STITCH