Targets of perturbagens

Perturbagen ID : CID51535

Perturbagen : (all-e)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid; 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl); Acide retinoique (french) (dsl); Agn 100335; All trans retinoic acid; All trans-retinoic acid; All-(e)-retinoic acid; All-trans-beta-retinoic acid; All-trans-retinoic acid; All-trans-tretinoin; All-trans-vitamin a acid; All-trans-vitamin a1 acid; Atra; Atralin; Avita; Beta-retinoic acid; Biacna topical gel; Clindamycin phosphate and tretinoin; Eudyna; Refissa; Refissa tretinoin (emollient); Rejuva-a; Renova; Retin-a; Retin-a micro; Retinoic acid; Retionic acid; Retisol-a; Ro 1-5488; Solagé; Stieva-a; Stieva-a cream; Stieva-a gel; Stieva-a solution; Trans-retinoic acid; Tretin m; Tretin.x; Tretinoin; Tretinoin cream; Tretinoin gel; Tretinoin gel microsphere; Tretinoina; Tretinoine (french) (einecs); Tretinoinum; Tretinx; Trétinoïne; Veltin; Vesanoid; Vitamin a acid; Ziana; Zo complex a tretinoin (emollient)

Target	Effect	Reference
ALDH1A1	-1	STITCH; DrugBank
ALDH3A1	-1	STITCH
CASP3	-1	STITCH
CCND1	-1	STITCH
CCNH	-1	STITCH
CYP1A2	-1	STITCH
CYP26A1	-1	STITCH; DrugBank
CYP26B1	-1	STITCH; DrugBank
CYP2C9	-1	STITCH
CYP2D6	-1	STITCH
EGF	-1	STITCH
GDNF	-1	STITCH
IFNG	-1	STITCH
IGF2	-1	STITCH
IL2	-1	STITCH
IL4	-1	STITCH
IL5	-1	STITCH
IL6	-1	STITCH
KIT	-1	STITCH
MMP2	-1	STITCH
NCOR1	-1	STITCH
NR1I3	-1	STITCH
PRAME	-1	STITCH
rplJ	-1	DrugBank
TERT	-1	STITCH
TGFB1	-1	STITCH
AKT1	1	STITCH
ALDH1A2	1	CLUE; STITCH; DrugBank
ALPL	1	STITCH
ARL6IP5	1	STITCH
CA2	1	STITCH
CASP7	1	STITCH
CASP8	1	STITCH
CASP9	1	STITCH
CDK4	1	STITCH
CEBPA	1	STITCH
CEBPB	1	STITCH
CRABP1	1	STITCH
CRABP2	1	STITCH
CREB1	1	STITCH
CXCL8	1	STITCH
CYP3A4	1	STITCH
GPRC5A	1	STITCH; DrugBank; CLUE
GPX2	1	STITCH
HGF	1	STITCH
HSD17B1	1	STITCH
IL10	1	STITCH
INS	1	STITCH
IRF1	1	STITCH
JUN	1	STITCH
LCN2	1	STITCH
LCP2	1	STITCH
MAP2K1	1	STITCH
MAP2K2	1	STITCH
MAPK1	1	STITCH
MAPK3	1	STITCH
NOS3	1	STITCH
NR0B1	1	CLUE; STITCH; DrugBank
NR1H4	1	STITCH
NR1I2	1	STITCH
NR2C2	1	CLUE; STITCH
NR6A1	1	STITCH
PDCD4	1	STITCH
PPARD	1	CLUE; STITCH
PPARG	1	STITCH
RAF1	1	STITCH
RARA	1	STITCH; DrugBank; CLUE
RARB	1	STITCH; DrugBank; CLUE
RARG	1	DrugBank; STITCH; CLUE
RARRES1	1	DrugBank; STITCH; CLUE
RB1	1	STITCH
RBP4	1	STITCH; DrugBank
RET	1	STITCH
RORB	1	CLUE; STITCH
RORC	1	CLUE; STITCH
RXRA	1	STITCH; DrugBank
RXRB	1	DrugBank; STITCH; CLUE
RXRG	1	DrugBank; STITCH; CLUE
SP1	1	STITCH
STAT1	1	STITCH
STS	1	STITCH
TGFB2	1	STITCH
TGM2	1	STITCH
TNF	1	STITCH
TP53	1	STITCH
VEGFA	1	STITCH
ABCB1	2	STITCH
ADH1B	2	STITCH
ALB	2	STITCH
ALDH1A3	2	STITCH
ANGPT2	2	STITCH
AOX1	2	STITCH
APLP1	2	STITCH
APLP2	2	STITCH
APP	2	STITCH
BAD	2	STITCH
BAX	2	STITCH
BCL2	2	STITCH
CCNA1	2	STITCH
CCNE1	2	STITCH
CDK2	2	STITCH
CDKN1B	2	STITCH
CSF1R	2	STITCH
CXCL16	2	STITCH
CYP1A1	2	STITCH
CYP26C1	2	DrugBank; STITCH
CYP2A13	2	STITCH
CYP2A6	2	STITCH
CYP2A7	2	STITCH
CYP2B6	2	STITCH
CYP2C18	2	STITCH
CYP2C8	2	STITCH
CYP2F1	2	STITCH
CYP2J2	2	STITCH
CYP2S1	2	STITCH
CYP3A5	2	STITCH
CYP3A7	2	STITCH
CYP4A11	2	STITCH
CYP4A22	2	STITCH
CYP4B1	2	STITCH
CYP4F11	2	STITCH
CYP4F12	2	STITCH
CYP4X1	2	STITCH
CYP4Z1	2	STITCH
DFFA	2	STITCH
F5	2	STITCH
FLT3	2	STITCH
H3-4	2	STITCH
H4-16	2	STITCH
HIST3H3	2	STITCH
HIST4H4	2	STITCH
HPGDS	2	DrugBank; STITCH
LCN1	2	DrugBank; STITCH
MET	2	STITCH
MGAT5	2	STITCH
MMP1	2	STITCH
MNAT1	2	STITCH
MYF6	2	STITCH
NCOA3	2	STITCH
NFKBIA	2	STITCH
NFKBIB	2	STITCH
NR1H2	2	STITCH
NR1H3	2	STITCH
OBP2A	2	DrugBank; STITCH
PAEP	2	STITCH
PARP1	2	STITCH
PDK4	2	DrugBank; STITCH
PML	2	STITCH
PRDX2	2	STITCH
PRKCA	2	STITCH
PRKCB	2	STITCH
PTK2	2	STITCH
RAB27A	2	STITCH
RBL2	2	STITCH
RORA	2	STITCH
SKP2	2	STITCH
SLC25A4	2	STITCH
SLC25A6	2	STITCH
SMAD2	2	STITCH
SMAD3	2	STITCH
SOX17	2	STITCH
TGFA	2	STITCH
TRIM16	2	STITCH
TTR	2	STITCH
UGT1A1	2	STITCH
UGT1A10	2	STITCH
UGT1A3	2	STITCH
UGT1A4	2	STITCH
UGT1A5	2	STITCH
UGT1A6	2	STITCH
UGT1A7	2	STITCH
UGT1A8	2	STITCH
UGT1A9	2	STITCH
UGT2A3	2	STITCH
UGT2B10	2	STITCH
UGT2B11	2	STITCH
UGT2B15	2	STITCH
UGT2B17	2	STITCH
UGT2B4	2	STITCH
UGT2B7	2	STITCH
VDR	2	STITCH
XAB2	2	STITCH