Targets of perturbagens

Perturbagen ID : CID51339

Perturbagen : (1s,3r,7s,8s,8ar)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2r,4r)-(tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyl (s)-2-methyl-butyrate; 2beta,6alpha-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone; 6-alpha-methylcompactin; 6alpha-methylcompactin; 6α-methylcompactin; Act lovastatin; Advicor; Altoprev; Ava-lovastatin; Dom-lovastatin; Lovastatin; Lovastatin-20; Lovastatin-40; Lovastatina; Lovastatine; Lovastatinum; Mevacor; Mevinolin; Mylan-lovastatin; Nu-lovastatin tablets; Phl-lovastatin; Pms-lovastatin; Pro-lovastatin; Ran-lovastatin; Ratio-lovastatin; Riva-lovastatin; Sandoz lovastatin; Teva-lovastatin

Target	Effect	Reference
ABCB1	-1	STITCH
ABCB11	-1	STITCH
CDK2	-1	STITCH
CYP2C8	-1	STITCH
CYP3A5	-1	CLUE; STITCH
HDAC2	-1	CLUE; STITCH; DrugBank
HMGCR	-1	DrugBank; CLUE; STITCH
HRAS	-1	STITCH
ITGAL	-1	CLUE; STITCH; DrugBank
MAPK1	-1	STITCH
MAPK3	-1	STITCH
NR1I2	-1	CLUE; STITCH
RAC1	-1	STITCH
RAF1	-1	STITCH
SLCO1B1	-1	STITCH
AKT1	1	STITCH
APOB	1	STITCH
CASP2	1	STITCH
CASP3	1	STITCH
CASP6	1	STITCH
CASP8	1	STITCH
CASP9	1	STITCH
CYP2C9	1	STITCH
FDFT1	1	STITCH
HCAR2	1	DrugBank
HCAR3	1	DrugBank
LDLR	1	STITCH
SREBF2	1	STITCH
AKAP7	2	STITCH
ANK2	2	STITCH
APOA1	2	STITCH
CYP3A4	2	STITCH
CYP3A7	2	STITCH
EAF2	2	STITCH
GSK3B	2	STITCH
KRAS	2	STITCH
LMNA	2	STITCH
LMNB1	2	STITCH
LPIN2	2	STITCH
NNMT	2	DrugBank
NRAS	2	STITCH
PARVB	2	STITCH
PON3	2	STITCH
QPRT	2	DrugBank
RASD1	2	STITCH
RB1	2	STITCH
RHOA	2	STITCH
RHOB	2	STITCH
STEAP2	2	STITCH
TG	2	STITCH
TNFSF10	2	STITCH