Targets of perturbagens

Perturbagen ID : CID51328

Perturbagen : [(1r)-3-methyl-1-({(2s)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid; Act bortezomib; Bortezomib; Bortezomib for injection; N-[(1r)-1-(dihydroxyboryl)-3-methylbutyl]-n-(pyrazin-2-ylcarbonyl)-l-phenylalaninamide; Pms-bortezomib; Velcade

Target	Effect	Reference
ABCB1	-1	STITCH
AKT1	-1	STITCH
CDK2	-1	STITCH
DKK1	-1	STITCH
EIF2AK3	-1	STITCH
ESR1	-1	STITCH
MAPK1	-1	STITCH
MAPK3	-1	STITCH
PSMA1	-1	CLUE; STITCH
PSMA2	-1	CLUE; STITCH
PSMA3	-1	CLUE; STITCH
PSMA4	-1	CLUE; STITCH
PSMA5	-1	CLUE; STITCH
PSMA6	-1	CLUE; STITCH
PSMA7	-1	CLUE; STITCH
PSMA8	-1	CLUE; STITCH
PSMB1	-1	DrugBank; CLUE; STITCH
PSMB10	-1	CLUE; STITCH
PSMB11	-1	CLUE; STITCH
PSMB2	-1	CLUE; STITCH
PSMB3	-1	CLUE; STITCH
PSMB4	-1	CLUE; STITCH
PSMB5	-1	DrugBank; CLUE; STITCH
PSMB6	-1	CLUE; STITCH
PSMB7	-1	CLUE; STITCH
PSMB8	-1	CLUE; STITCH
PSMB9	-1	CLUE; STITCH
PSMD1	-1	CLUE; STITCH
PSMD2	-1	CLUE; STITCH
RELA	-1	CLUE; STITCH
XBP1	-1	STITCH
ABCC2	1	STITCH
BCL2L11	1	STITCH
BIK	1	STITCH
CASP2	1	STITCH
CASP3	1	STITCH
CASP4	1	STITCH
CASP7	1	STITCH
CASP8	1	STITCH
CASP9	1	STITCH
CDK1	1	STITCH
CDKN1A	1	STITCH
CDKN1B	1	STITCH
CXCL8	1	STITCH
CYCS	1	STITCH
HMOX1	1	STITCH
HSPA1A	1	STITCH
HSPA1B	1	STITCH
HSPA5	1	STITCH
JUN	1	STITCH
MAP2K4	1	STITCH
MAPK8	1	STITCH
MCL1	1	STITCH
PARP1	1	STITCH
PMAIP1	1	STITCH
STK4	1	STITCH
TNFRSF10A	1	STITCH
TNFRSF10B	1	STITCH
TNFSF10	1	STITCH
TP53	1	STITCH
ABCB4	2	STITCH
ABCC1	2	STITCH
ABCC3	2	STITCH
ABCC4	2	STITCH
ABCC6	2	STITCH
AHR	2	STITCH
AIFM1	2	STITCH
ALOX12	2	STITCH
ANGPTL4	2	STITCH
APOB	2	STITCH
ARVCF	2	STITCH
ATF2	2	STITCH
ATF3	2	STITCH
ATF4	2	STITCH
ATM	2	STITCH
BAK1	2	STITCH
BAX	2	STITCH
BCL2	2	STITCH
BCL2L1	2	STITCH
BECN1	2	STITCH
BID	2	STITCH
BMPR1B	2	STITCH
BRCA1	2	STITCH
CASP6	2	STITCH
CD27	2	STITCH
CDC6	2	STITCH
CES1	2	STITCH
CETP	2	STITCH
CFLAR	2	STITCH
CHEK1	2	STITCH
CKM	2	STITCH
CPT1C	2	STITCH
CSF2	2	STITCH
CTNNB1	2	STITCH
CTSB	2	STITCH
CYP24A1	2	STITCH
CYP4F12	2	STITCH
DBH	2	STITCH
DCK	2	STITCH
DDIT3	2	STITCH
DDIT4L	2	STITCH
DIABLO	2	STITCH
DPF3	2	STITCH
DPYD	2	STITCH
DUSP13	2	STITCH
DUSP23	2	STITCH
EDN1	2	STITCH
EGF	2	STITCH
EIF2A	2	STITCH
EIF2S1	2	STITCH
EPHX1	2	STITCH
ERBB2	2	STITCH
ERCC2	2	STITCH
ERCC3	2	STITCH
ERCC4	2	STITCH
ERN1	2	STITCH
EXO1	2	STITCH
FMO2	2	STITCH
FMO3	2	STITCH
FRMD4B	2	STITCH
FRY	2	STITCH
GAD1	2	STITCH
GHR	2	STITCH
GPANK1	2	STITCH
GSTP1	2	STITCH
GZMH	2	STITCH
HCLS1	2	STITCH
HDAC6	2	STITCH
HELQ	2	STITCH
HSPB1	2	STITCH
HUS1	2	STITCH
IFNGR2	2	STITCH
IGF1R	2	STITCH
IGF2	2	STITCH
IL17RD	2	STITCH
IL18	2	STITCH
IL1RN	2	STITCH
IL2	2	STITCH
IL3	2	STITCH
IL6	2	STITCH
IRF4	2	STITCH
IRS1	2	STITCH
ITGBL1	2	STITCH
KIAA1324	2	STITCH
KLHDC8A	2	STITCH
LEPR	2	STITCH
LMF1	2	STITCH
LMNA	2	STITCH
LSM1	2	STITCH
LTK	2	STITCH
MAPK9	2	STITCH
MBD6	2	STITCH
MBL2	2	STITCH
MERTK	2	STITCH
MFHAS1	2	STITCH
MN1	2	STITCH
MRE11	2	STITCH
MSH6	2	STITCH
MTHFR	2	STITCH
MTR	2	STITCH
MUTYH	2	STITCH
MYO5A	2	STITCH
NAT1	2	STITCH
NEIL3	2	STITCH
NEK4	2	STITCH
NFKB2	2	STITCH
NFKBIA	2	STITCH
NFKBIB	2	STITCH
NFKBIE	2	STITCH
NPM1	2	STITCH
OSBPL6	2	STITCH
OSGEP	2	STITCH
PARP2	2	STITCH
PIK3CG	2	STITCH
PINK1	2	STITCH
PLAUR	2	STITCH
POU2F2	2	STITCH
PPARD	2	STITCH
PPARGC1A	2	STITCH
PPIA	2	STITCH
PPP3CA	2	STITCH
PPP4R1	2	STITCH
PRKD3	2	STITCH
PRKDC	2	STITCH
PTPRN2	2	STITCH
RAB37	2	STITCH
RAPH1	2	STITCH
RASGRP1	2	STITCH
RHOBTB2	2	STITCH
SELP	2	STITCH
SERPINB2	2	STITCH
SGPP1	2	STITCH
SLC22A8	2	STITCH
SOD2	2	STITCH
SOX8	2	STITCH
SRD5A1	2	STITCH
STAT6	2	STITCH
STK31	2	STITCH
SULT4A1	2	STITCH
SUSD4	2	STITCH
TAP2	2	STITCH
TCF7L1	2	STITCH
TICRR	2	STITCH
TLR4	2	STITCH
TNF	2	STITCH
TRERF1	2	STITCH
TRPS1	2	STITCH
TSPO	2	STITCH
TTLL12	2	STITCH
UACA	2	STITCH
VEGFA	2	STITCH
VWF	2	STITCH
WEE1	2	STITCH
WNK1	2	STITCH
WRN	2	STITCH
XIAP	2	STITCH
ZNF385B	2	STITCH